Modeling yeast population dynamics in space environments using agent-based modeling and genetic algorithm

Authors

  • Maria Lourdes C. Balane ⋅ PH National Institute of Physics, University of the Philippines Diliman
  • Celso T. Villano Jr. ⋅ PH Computational Science Research Center, University of the Philippines Diliman
  • Dominic P. Guaña ⋅ PH Philippine Space Agency
  • Reinabelle C. Reyes ⋅ PH Philippine Space Agency and Research Center for Theoretical Physics, Central Visayan Institute Foundation
  • Gay Jane P. Perez ⋅ PH Philippine Space Agency and Institute of Environmental Science and Meteorology, University of the Philippines Diliman

Abstract

We demonstrate how computational simulations of yeast (Saccharomyces cerevisiae) colony growth using a hybrid model that combines cellular automata and genetic algorithms can provide insights into the potential effects of initial radiation resistance and radiation-induced genetic mutations. Our preliminary results suggest that initial radiation resistance is a critical determinant of population survival, whereas increasing the probability of radiation-induced mutations appears to have limited impact on yeast growth. While these results are based on a limited number of simulations, they offer initial insights that can guide future, more comprehensive investigations on the complex role of radiation on yeast populations.

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Issue

Entangled!
25-28 June 2025, National Institute of Physics, University of the Philippines Diliman

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Article ID

SPP-2025-2G-04

Section

Complex Systems and Data Analytics

Published

2025-06-22

How to Cite

[1]
MLC Balane, CT Villano, DP Guaña, RC Reyes, and GJP Perez, Modeling yeast population dynamics in space environments using agent-based modeling and genetic algorithm, Proceedings of the Samahang Pisika ng Pilipinas 43, SPP-2025-2G-04 (2025). URL: https://proceedings.spp-online.org/article/view/SPP-2025-2G-04.