Effect of temporal and spatial resolution on the apparent diffusion coefficient and mean free path of a Brownian particle
Abstract
We investigate the effect of the temporal and spatial resolution on the apparent motion of a Brownian particle. A set of particle trajectories were resampled at varying time intervals and spatial resolutions. The diffusion coefficients and mean free paths were measured from the resampled data. We find that the apparent diffusion coefficient does not depend on the sampling time, while the apparent mean free path increases with the square root of the sampling time. The apparent diffusion coefficient and mean free path remain constant only in the nanometer range of spatial resolution and deviates from the expected value at larger spatial resolutions.