Quasi-periodic amplitude masks for light sheet fluorescence microscopy: An exploration in nature-inspired design

Abstract

Quasi-periodic structures offer promising potential in diverse applications, such as lithography, X-ray microscopy, and three-dimensional optical tweezers. To extend this exploration, we focus on the potential of such structures for light sheet generation in light sheet fluorescence microscopy (LSFM). Drawing inspiration from nature, we materialize the inherent properties of an m-bonacci sequence to an amplitude mask. To validate its efficacy, we conduct a comprehensive comparison with its more conventional, periodically structured counterparts. By exploring the differences and similarities in the light sheets produced by each mask, we provide clear evidence supporting the viability and advantages of our nature-inspired design.