Impact of the absorption and reflection of signals on the radiation-induced bystander effect

Authors

Zheina Ottong ⋅ PH National Institute of Physics, University of the Philippines Diliman
Cristine Villagonzalo ⋅ PH National Institute of Physics, University of the Philippines Diliman

Abstract

The radiation-induced bystander effect (RIBE) implies radiation risks to cells or tissues not directly exposed to radiation. Effects were found to be strong in the low-dose range which humans are exposed to in the environment such as in medical activities and unpredicted accidents. One possible mechanism of RIBE is through signal transmission between irradiated cells and non-irradiated cells. This work modeled signal transmission through a 2D random walk (RW) of signals in a cell-culture medium containing 103 non-irradiated cells. The effect of boundary conditions (reflection vs. absorption) were observed. Results for the reflection case was better suited for experimental data than the absorption case. It showed independence of RIBE with distance from irradiated source.

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Issue

2018: Proceedings of the 36th Samahang Pisika ng Pilipinas Physics Conference

Article ID

SPP-2018-PC-22

Section

Poster Session C (Mathematical Physics, Optics, and Interdisciplinary Topics)

Published

2018-05-24

How to Cite

[1]

Z Ottong and C Villagonzalo, Impact of the absorption and reflection of signals on the radiation-induced bystander effect, Proceedings of the Samahang Pisika ng Pilipinas 36, SPP-2018-PC-22 (2018). URL: https://proceedings.spp-online.org/article/view/SPP-2018-PC-22.