O₂ plasma treatment of electrospun Hydroxyapatite/Chitosan-PCL bioscaffold for bone tissue engineering
Abstract
Biocomposite scaffolds from hydroxyapatite, chitosan and poly(εcaprolactone) was prepared by electrospinning. Oxygen plasma treatment was used to modify the scaffold surface at a fixed 150W microwave power and 180s treatment time. The synthesized HA and electrospun scaffolds were evaluated using SEM, FTIR, and XRD analyses. Results confirm HA formation with the appearance of its characteristic O-H and P-O bands, and 2ϴ peaks. Comparison of the untreated and plasma-treated scaffolds also show no chemical changes. However, ablations from plasma cleaning and etching increased the surface roughness. Mean fiber diameters decreased from 4.89 ± 3.32µm (untreated) to 2.58 ± 2.45 µm (plasma-treated).